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English Audio Request

yin1441
145 Words / 1 Recordings / 2 Comments

Host genetics seems to play a major role on the development of the virus systemic disease. Landrace pigs, for example, develop more severe lymphoid lesions and clinical disease than Duroc, Large White and Pietrain pigs. Hampshire boars, on the other side, have less clinical signs occurrence of the disease. To sum up, there's a clear link between genetics and clinical expression. Anyway, there's no knowledge on the mechanisms that may cause this.

Porcine circovirus 2 is genetically stable and has a long-lasting infection in the individual host. Usually pigs are infected by several genetically related strains for the same genotype. It's posible too to have a co-infection. It's suspected that this virus presents a quasi-species structure. This means that the virus can show different mutations in a same animal. To confirm that point it would be necessary to do extensive sequencing analyses in different individuals.

Recordings

  • Porcine circovirus 2 (Part 2) ( recorded by GlobalWarning ), Standard English (RP)

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    Host genetics seems to play a major role in the development of the viral systemic disease. Landrace pigs, for example, develop more severe lymphoid lesions and clinical disease than Duroc, Large White and Pietrain pigs. Hampshire boars, on the other side, have fewer clinical signs occurrence of the disease. To sum up, there's a clear link between genetics and clinical expression. To date, nothing is known of the mechanisms that may cause this.

    Porcine circovirus 2 is genetically stable and produces a long-lasting infection in the individual host. Usually, pigs are infected by several genetically-related strains for the same genotype. It's possible, too, to have a co-infection. It's suspected that this virus presents a quasi-species structure. This means that the virus can show different mutations in the same animal. To confirm that point it would be necessary to do extensive sequencing analyses in different individuals.

Comments

GlobalWarning
Jan. 10, 2017

If you don't like my text alterations, please comment, and I will record again. Good luck with your work.

yin1441
Jan. 11, 2017

Thank you very much, it will help me a lot!

Overview

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